Cannabigerol (CBG)

Definition: Cannabigerol (CBG) is a non-intoxicating cannabinoid. Its acid form, CBGA, is the starting compound the cannabis plant converts into THCA, CBDA, and other cannabinoid acids. Most mature cannabis contains only small amounts of CBG, though breeders have developed high-CBG hemp. Early lab research is interesting, but human evidence is limited.

Why Is CBG Called the “Mother Cannabinoid”?

Inside the plant’s trichomes, enzymes turn CBGA into THCA and CBDA. By harvest, most CBGA has already been converted, which is why CBG levels are usually low. When CBGA is heated, it decarboxylates into CBG, just as THCA becomes THC.

Does CBG Get You High?

No. CBG doesn’t produce the high associated with THC. Lab studies show it interacts with several targets, including cannabinoid receptors and alpha-2 adrenergic receptors, but those findings don’t automatically translate into effects you’d notice.

What Does CBG Do?

In lab and animal research, CBG has shown antibacterial activity, including against MRSA, plus anti-inflammatory and other properties. Those are early findings. There are few human clinical trials, and the FDA hasn’t approved CBG to treat any condition. Be skeptical of products that promise specific health benefits.

Where Do You Find CBG?

CBG is sold in oils, tinctures, gummies, and high-CBG hemp flower. Check a certificate of analysis to confirm the CBG content and make sure the product doesn’t contain more THC than labeled.

Related terms: Cannabinoids, Cannabinol (CBN), THCA, Full Spectrum, Broad Spectrum, and Isolate

Sources: Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 2011 (PMC); PubChem: Cannabigerol (CID 5315659).

This entry is for general education and isn’t medical advice.