The Entourage Effect

The term “entourage effect” was coined by Israeli chemist and pharmacologist Dr. Raphael Mechoulam in 1999. Dr. Mechoulam is considered to be the father of cannabis research, and he has made significant contributions to our understanding of the plant’s chemistry and biology.

Dr. Mechoulam hypothesized that the entourage effect was due to the interaction between cannabinoids and other compounds in cannabis, such as terpenes and flavonoids. He believed that these compounds worked together to produce a more potent and synergistic effect than any of the compounds alone.

The entourage effect is still under scientific investigation, but there is growing evidence to support Dr. Mechoulam’s hypothesis. For example, studies have shown that combinations of cannabinoids and terpenes can be more effective at treating pain, inflammation, and anxiety than either compound alone.